A randomized controlled trial conducted during the H1N1 pandemic found “Influenza transmission was not reduced by… hand washing and face mask use.”5 5. A randomized controlled trial (RCT) is considered as the gold standard to infer the effect of the exposure on the outcome 10. Randomized controlled trials have greatly expanded in the last two decades • Randomized controlled Trials were progressively accepted as a tool for policy evaluation in the US through many battles from the 1970s to the 1990s. However, they are not easy to conduct and have a number of aspects to be looked into. An RTC of pilgrims sleeping The randomized controlled trial is the most rigorous and robust … Fig. Randomized controlled trials (RCTs) are the gold standard in terms of study design, however, in the surgical setting conducting RCTs can often be unethical or logistically impossible. research; randomised controlled trials; The randomised control trial (RCT) is a trial in which subjects are randomly assigned to one of two groups: one (the experimental group) receiving the intervention that is being tested, and the other (the comparison group or control) receiving an alternative (conventional) treatment (fig 1). 2: Flow diagram of the progress through the phases of a parallel randomized trial of two groups [6] Randomized Controlled Field Trial: It is similar to an Randomized Controlled Clinical Trial except that the intervention is preventive and not therapeutic. • In development, the rapid growth starts after the mid 1990s – … 4. 1- Example of a Randomized Controlled Clinical Trial [7] Fig. A 19-month randomized controlled trial found a reduction in respiratory infection through educational interventions; but no reduction when adding masks.6 6. A randomized controlled trial is a prospective, comparative, quantitative study/ experiment performed under controlled conditions with random allocation of interventions to comparison groups.

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